“You can then sequence that particular phage clone, and it will tell you the nucleotide sequence and therefore ... “It’s not random,” said Anthony Kossiakoff, a protein engineer at the University of ...

The sequence of amino acids in the chain determines how the chain will fold up to make the protein, so different proteins have different three-dimensional shapes. The three-dimensional shape of a ...

RNA breaks destined for repair are inflicted by sequence-specific or structure-specific endoribonucleases during physiological RNA ... If Pnkp and Rnl1 are not present, depletion of the pool of ...

Although the rational protein design approach offers an increased possibility of beneficial alterations, it is not easy to accurately predict the sequence-structure-function relationship, particularly ...

Viruses known as “jumbo phage” are a new hope against the rising antibacterial infection crisis. Researchers have discovered ...

Gerd Prehna and his lab have been studying the phage protein paratox (Prx). Two graduate students, Tasneem Hassan Muna and Nicole Rutbeek from the Prehna Lab have discovered that phages use ...

To fend off phage attacks, bacteria have evolved their ... have studied the BREX methyltransferase and determined the protein structure, which helped to program its specificity for DNA sites ...