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Proficient structural biologists consider more than the library. “The biggest thing about any of these selections is the quality of the antigen,” Kossiakoff said. He explained that for phage display ...
Then they transform the plasmids into a bacterial vector and infect it with a helper phage that supplies the other necessary viral proteins. This generates the phage library, where each virion ...
In this issue, Gishizky and coworkers describe yet another use for phage display—a method for mapping protein–protein interactions that is faster than two-hybrid systems and that allows the ...
Filamentous bacteriophage fd can display multiple copies of foreign peptides in the N-terminal region of its major coat protein pVIII, 2,700 copies of which make up the virus capsid. Here we show ...
来自MSN8 个月
Phage display technology effectively improves specific targeting ability of anti-microbial ...In a new study, researchers have screened nine heptapeptide sequences from a random peptide library using phage display technology, with S. aureus 6538 as the target bacterium. The work is ...
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