Physiological extracellular matrix (ECM) calcification or mineralization is restricted to bones, teeth and the hypertrophic zone of growth plate cartilage. In contrast, pathological ECM ...

inclusion of targeted calcifications. Pathologic result yielded estrogen receptor (ER)-positive, progesterone receptor (PR)-positive, and human epidermal growth factor receptor 2 (HER2)-negative ...

and aortic valve calcification, all diseases seen in the elderly. The process of aging is a continuum progressing throughout the individual's life. Unlike pathologic conditions, the aging process ...