Targeting mitochondrial retrograde signaling may therefore be promising in the treatment or prevention of metabolic disorders ...

Researchers at the University of Michigan used mice to show that dysfunctional mitochondria trigger a response that affects ...

List of Confirmed and Putative Signal Transducer and Activator of Transcription (STAT)5-Target Genes in β-cells or Pancreatic Islets (Activated or Repressed Genes) Target genes of prolactin or ...

胰腺癌（Pancreatic Ductal Adenocarcinoma, PDAC）因其高度侵袭性和极低的生存率，被认为是最具挑战性的癌症之一。尽管近年来免疫治疗技术迅速发展，许多肿瘤仍然被归类为“免疫冷”的状态，意味着肿瘤微环境中缺乏足够的免疫细胞浸润，使得治疗效果受限。然而，研究人员近年来的研究揭示了一个可能突破这一瓶颈的关键——三级淋巴结构（Tertiary Lymphoid Struct ...

Signal transducer and activator of transcription (STAT)5A and -5B are latent transcription factors expressed in pancreatic β-cells and other tissues. Prolactin and growth hormone binding to their ...

Pancreatic cancer patients may benefit from future precision treatments as a new study shows how some tumors may potentially ...

Mitochondria are essential for generating energy that fuels cells and helps them function. Mitochondria are essential for generating energy that fuels cells and helps them function.

Conceptual diagram summarizing the central experiment comparing cell death in amyloid-β treated neuronal cells with and without pancreatic β cell culture supernatant. Pancreas cells may produce ...

The researchers were able to recreate a complete structure that includes the three key cell types in the pancreas, which previous organoids couldn't fully mimic. Notably, the team identified a new ...

Jan. 6, 2025 — Researchers have developed a way of detecting circulating tumor cells in the bloodstream of pancreatic cancer and lung cancer ... Enzyme Promoting Tumor Growth and Spread in ...