资讯

生物通15 天
靶向PRDX2通过调控FN1和PI3K/AKT/SP1通路抑制三阴性乳腺癌生长转移的 ...
编辑推荐：针对三阴性乳腺癌(TNBC)高转移性难题，中国科技大学团队发现抗氧化酶PRDX2通过激活PI3K/AKT/SP1信号轴促进FN1表达 ...
Medscape1 天
Hyperglycemia: A Risky Side Effect of Certain Cancer Drugs
The frequency of high blood glucose among patients receiving PI3K/Akt inhibitors to treat breast cancer has some oncologists ...
生物通7 天
ITGA5通过PI3K/AKT/mTORC1通路诱导间质转化促进胶质瘤进展的机制研究
本研究针对胶质瘤恶性进展的分子机制，聚焦整合素家族成员ITGA5，通过生物信息学分析结合实验验证，揭示了ITGA5通过激活 ...
eLife5 天
DuoHexaBody-CD37 induces direct cytotoxic signaling in diffuse large B-cell lymphoma
This study presents a valuable finding on the direct cytotoxic effects of DuoHexaBody-CD37 in diffuse large B-cell lymphoma, mediated via SHP-1 activation and antibody clustering, independent of ...