IDX-1197 has several key advantages over those commercially available PARP inhibitors. Notably, IDX-1197 has a particularly strong trapping effect ... in 2017 (Fig. 1). The study reported clinical ...

Poly(ADP-ribose) polymerase (PARP) inhibitors (PARPis) are promising cancer treatments because they block a cell’s ability to repair DNA damage. Four PARPis are currently approved for use in the ...