Bilateral optic disc swelling is an important clinical sign ... of the nerve fiber layer hemorrhage from the swollen optic nerve head represents a point by which hypertensive retinopathy can ...

The hypothesis that it disrupts the function of retinal ganglion cell axons by increasing mechanical forces on the lamina cribrosa of the optic nerve head has received considerable experimental ...

A 9-year-old Saudi boy was referred for further management of "papilledema." Initial workup at the referring institution included computed tomography, which did not disclose any abnormal findings.

Cross-section of nerve fibers from the mouse optic nerve: The dark dense lines show the insulating layer, the myelin. Highlighted in red is a swollen, clogged area of an impaired nerve fiber ...