The FDA has granted fast-track designation to an investigational antisense oligonucleotide to treat individuals with myotonic ...

After raising questions surrounding dosing levels, the FDA has freed Amylyx’s early-stage amyotrophic lateral sclerosis (ALS) ...

Oligonucleotide probes are short stretches of single-stranded DNA or RNA used to detect the presence of complementary nucleic acid sequences (target sequences) by hybridization. Oligonucleotide ...

Our expert speakers will also discuss how to apply the Oligo Analysis Accelerator for OpenLabs CDS to your oligonucleotide therapeutic testing, helping you to optimize synthesis and purification.

India-based Suven Pharmaceuticals has announced a definitive agreement to acquire a strategic controlling stake in Sapala ...

Scientists have developed a new approach to produce life-saving oligonucleotide therapeutics on a large scale, in high purity, and with minimal environmental impacts. Therapeutic oligonucleotides are ...

The global Oligonucleotide CDMO Market, valued at US$2.33 billion in 2023, is forecasted to grow at a robust CAGR of 21.8%, ...

(3) Chemicals cap unreacted 5’-hydroxyl groups. An oxidation step creates a more stable coupling. The oligonucleotide is ready for another round of synthesis. (4) Chemicals stabilize coupling. Once ...

Despite the increasing focus on short oligonucleotide therapeutics, standardized methods to rigorously characterize the structure of these molecules, which is essential for drug development and ...

Amylyx Pharmaceuticals Announces FDA Has Lifted the Clinical Hold on AMX0114 Phase 1 Clinical Trial for the Treatment of ALS ...