This study utilized high-throughput Affymetrix microarrays to identify gene expression changes in the post-mortem nucleus accumbens of chronic heroin abusers. These data were analyzed ...

New research uncovers how dopamine in the ventral shell of the nucleus accumbens (vsNAc) governs the sexual behavior sequence in male mice, from sniffing to ejaculation.

The brain constantly evaluates whether stimuli are positive or negative, prompting approach or avoidance behaviors that are essential for survival.

Once consumed, the drug delivers a powerful stimulus to the nucleus accumbens, a cluster of nerve cells below the cerebral cortex, which responds quickly by releasing a flood of dopamine.

Adenosine A 2A receptors (A 2A R) in the nucleus accumbens of the brain play an important role in regulating sleep and motivation, but until now, no drugs have been able to selectively modulate ...

A Phase I clinical trial shows that deep brain stimulation (DBS) targeting the nucleus accumbens (NAc) is safe and feasible ...