Inhibitors of DNA methylation can reactivate genes that ... These medications work by acting like the nucleotide cytosine and incorporating themselves into DNA while it is replicating.

Methylation of cytosines in CpG dinucleotides ... For every successful nucleotide incorporation, pyrophosphate (PPi) is released. PPi is converted in enzyme-catalyzed reactions to drive light ...

DNA methylation is a fundamental epigenetic mechanism in which a methyl group is added onto a nucleotide, commonly cytosine. DNA methylation affects many biological processes, including gene ...