CT-guided biopsy 9 days later demonstrated significant progression of the granulomatous lesions. Histopathological analysis revealed extensive necrotizing epithelioid cell granulomatosis.

The pathology of WG/GPA is characteristically described as a granulomatous necrotizing inflammation and pauci-immune vasculitis of the small- to medium-sized blood vessels (Figure 1). WG/GPA can ...