Each of us has enough DNA to reach from here to the sun and back, more than 300 times. How is all of that DNA packaged so tightly into chromosomes and squeezed into a tiny nucleus? Histones are a ...

Concurrent analysis of whole-genome DNA methylation and single-cell RNA sequencing data from COVID-19 patients and controls ...

Chances are you've seen an illustration of DNA's double-helix structure and even pictures of the chromosomes that comprise the human genome. But where and how does the famous double helix fit into ...

We lysed cells in IPH buffer (1 ml; 50 mM Tris-HCl, pH 8.0, 150 mM NaCl, 5 mM EDTA, 0.5% NP-40, 0.1 mM PMSF ... Targeted mutation of the DNA methyltransferase gene results in embryonic lethality.