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Ketamine research may lead to safer treatments for depression, anxiety and other mental health conditions
"It's been suggested for over a decade that the drug blocks a specific kind of NMDA receptor (NMDAR), called GluN1-2B-2D." There was one big problem with this theory. Scientists weren't quite sure ...
Nature5y
195 The Selective Sigma-1 Receptor Agonist Pre-084 Reduces Ndmar- Mediated Excitotoxic Brain Injury in Newborn Mice
The aim of this study was to evaluate the effect of Pre-084 in NMDAR-mediated excitotoxic brain injury in newborn mice. Methods: 5-day-old mice pups were injected intracranially with ibotenate ...