Neurofibromatosis type 2 is caused by a change in the NF2 gene located on chromosome 22. This gene encodes a protein known as merlin. Mutations in the NF2 gene disrupt the function of merlin, which is ...
genetic testing can diagnose NF2 with 90% sensitivity by sequencing a person’s NF2 gene to identify mutations. The UAB Medical Genomics Laboratory offers the most scientifically reliable and advanced ...
Meningiomas, often linked to the loss of the NF2 gene, are a hallmark of NF2-SWN and can severely impact patients' lives despite being typically non-malignant. Through this new project ...
Key events in mesothelioma tumorigenesis encompass inactivation of the neurofibromatosis gene type 2 (NF2) and loss of INK4α/ARF, but other molecular mechanisms cannot be excluded. Inactivation ...