Neurofibromatosis type 2 is caused by a change in the NF2 gene located on chromosome 22. This gene encodes a protein known as merlin. Mutations in the NF2 gene disrupt the function of merlin, which is ...

The spotlight for the story was on Mya, a 15-year-old who lives life with neurofibromatosis, type 2 (NF2), a condition that causes spinal and brain tumors. As Mya and her mother told her story ...

The procedure is most often recommended for people with neurofibromatosis type 2 (NF2) who have noncancerous tumors on their auditory nerve, particularly when the tumor is removed, damaging the nerve.

Biomarker analyses showed that 14 of 24 patients with NF2 alterations met the PFS6 objective as compared with one of four patients with CDK variants and two of seven with both types of alterations ...

Open-label, Phase 2 Clinical Trial of Crizotinib for Children and Adults with Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas Crizotinib (Xalkori®), a small molecule kinase inhibitor, ...