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生物通
7 天
在氮限制条件下工程大肠杆菌中丙酮醇生物合成实现 NADPH 平衡
丙酮醇生物合成途径有助于维持细胞内的 NADPH/NADP + 平衡,在氮限制且无生物质形成的条件下 ... 1,2 - 丙二醇的生产,但同时需要解决 NADH 供应不足等问题,还可能需要通过适应性实验室进化来提高菌株对高浓度产物的耐受性。 这项研究为利用微生物细胞工厂 ...
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