N-Acetyltransferase 2 (NAT2 ... NAT2 polymorphisms can influence drug metabolism and the risk of adverse drug reactions, including hepatotoxicity. For instance, NAT2*4, *5B, and *7B were ...

Many of these genetic variants (i.e., genotypes) were discovered after observing adverse reactions (i.e., phenotypes ... review (e.g., CYP isoenzymes, N-acetyltransferase) are located primarily ...