No biological system has been studied by more diverse approaches than the actin-based molecular motor myosin. Biophysics, biochemistry, physiology, classical genetics and molecular genetics have ...

"These myosin motors are so universal in terms of cell types and motile cellular structures that studying them has a huge impact on many pathological processes like cancer and metastasis of the ...

Forcing one trajectory over another is no easier than moving through a cyclone. Yet, it is in this disordered environment that biological motors, proteins with complex structures, produce perfectly ...

Hypertrophic cardiomyopathy (HCM), a progressive inherited heart disease, is the leading cause of sudden death in young people. A prominent cause of HCM is mutations in cardiac myosin, a sarcomeric ...