By using embryonic stem cell engineering, the researchers were able to reprogram the imprinted genes, effectively allowing ...

They deactivated the Tgfbr1 gene in mouse embryos during mid-stage development to investigate its effects on the development of the spinal cord. The Tgfbr1 gene provides instructions for making a ...

The concept of biological reproduction between same-sex individuals in mammals has always been deemed impossible. However, ...

It’s a new way to create “bi-paternal” mice that can survive to adulthood—but human applications are still a long way off.

Early embryo development is a highly dynamic process that is of great interest to scientists, but most studies tend to focus on a single species, typically mouse or human. This study, however ...

This valuable study presents a mouse gastruloid model that can be used to generate hematopoietic progenitors as well as leukemic cells. However, in its current form, the manuscript is inadequate ...

As development continues, the epiblast invades inward toward the primitive endoderm ... a stem cell biologist at the Medical Research Council Laboratory of Molecular Biology who works with both stem ...

Using cutting-edge stem cell technology, a team of scientists from the Chinese Academy of Sciences (CAS) recently created a mouse with two biological fathers.

model to understand the physiological functions of SETD2 in mouse embryonic development. Both Setd2-CD and Setd2-KO mice exhibited embryonic lethality with similar vascular defects, indicating ...

Stem cell scientists have successfully used embryonic stem cell engineering to create a bi-paternal mouse — a mouse with two ...