Starting from the hypothesis that immune cells promptly respond to harmful stimuli, we used peripheral blood monocytes in order to characterise a distinct gene expression profile and to evaluate its ...

Objectives Bone destruction in rheumatoid arthritis is mediated by osteoclasts (OC), which are derived from precursor cells of the myeloid lineage. The role of the two monocyte subsets, classical ...

They used the chronic social defeat stress (CSDS) paradigm, a validated mouse model of psychosocial stress ... B cells and increased inflammatory monocytes and neutrophils in RES and SUS mice.

The computational model predicted the actual magnetic accumulation of the SPION-loaded cells ... Analogously to the previously published loading of T cells with SPIONs, we established the loading of ...

A Cox proportional hazards model was fitted to adjust for confounders ... We obtained strong evidence in support of neutrophil-to-lymphocyte ratio and lymphocyte-to-monocyte ratio as prognostic ...

In contrast, the resistant model had few monocytes, but was filled with suppressive macrophages, which are known to inhibit immune responses. "Monocytes were thought to play a limited role in ...

Objective Monocyte chemotactic protein-1-induced protein 1 (MCPIP1) is highly expressed in inflamed mucosa of inflammatory bowel disease (IBD) and negatively regulates immune response, while the ...