The manuscript addresses the 3D chromatin architecture in monocytes from patients with alcohol-associated hepatitis and its relationship to enhanced transcription of innate immune genes. While the ...

Medically reviewed by Doru Paul, MDMedically reviewed by Doru Paul, MD A high monocyte count (monocytosis) is a blood test finding that can indicate an infection, an autoimmune disease ...

Most of the children’s variants were in the gene’s transmembrane domain. Introduction of the variants into healthy cells abolished CCR2 protein expression, and the patients’ own monocytes lacked the ...