By uncovering how these histone modifications influence the brain, the team has identified a novel mechanism for controlling circadian gene expression and behavioral rhythms. The team's findings ...

A fluorescent probe designed to incorporate a fluorophore into the structure of a neurotransmitter finds activity-dependent heterogeneity in dopamine release at individual synapses ...

"Our findings emphasize that the brain's internal clock is influenced by chemical monoamine neurotransmitters in a manner not previously appreciated, such that monoamines can directly modify ...

For many years, the prevailing hypothesis of depression has been that a deficit in monoamine neurotransmitters, notably norepinephrine and serotonin, underlies depression. The monoamines are named ...

Inhibiting neurotransmitter degradation or neurotransmitter reuptake results in an increase in neurotransmitters in the synapse. This increase in monoamine neurotransmitter concentrations results ...