"This finding highlights a previously unknown connection between mitochondrial activity, inflammation control and the signaling pathways that regulate it," Chandel said. Overall, the findings ...

The scientists also discovered those mice with the defective mitochondrial complex also struggled to recover from infection and inflammation because their cells released less IL-10. However, ...

A team of researchers from the Keck School of Medicine of USC has unlocked the details of a cellular pathway that ... It also triggered inflammation and cellular senescence, a state common in ...

elegans mitochondrial factor WAH-1 promotes phosphatidylserine externalization in apoptotic ... Caenorhabditis elegans drp-1 and fis-2 Regulate Distinct Cell-Death Execution Pathways Downstream of ced ...

(1) Degradation of mitochondria matrix, inner membrane and intermembrane oxidised or misfolded protein by mitochondrial proteases. (2) Ubiquitinated outer mitochondrial membrane proteins are ...

Activating a specific reactive oxygen species (ROS) pathway restored IL-10 release. "This finding highlights a previously unknown connection between mitochondrial activity, inflammation control ...