A misfolded protein facilitates reliable diagnosis even in the early stages of Parkinson’s disease in body fluids.

Almost two decades have passed since Stanley Prusiner proposed that the transmissible agent causing spongiform encephalopathies consists of a misfolded protein — but the biology of prion ...

The function of a protein depends on the precise three-dimensional structure of its folded forms, but errors in the folding process occur and can have serious consequences. Two papers in April 4 ...

New probes detect protein aggregates in salivary gland samples from patients with familial amyloid neuropathy (arrows). Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of ...

"Either Sep15 is giving the misfolded protein a chance at correcting its shape, or it is marking that protein for destruction." "The complexity of the proteins we are studying allows higher forms ...

"Misfolded proteins can take on many different ... Offering a scalable, accurate method for analyzing the structure of harmful protein aggregates, RibbonFold opens new possibilities for drug ...

Scientists have developed a powerful new artificial intelligence tool that could change the way we understand and treat brain diseases like Alzheimer’s and Parkinson’s. The tool, called RibbonFold, ...

A new AI tool called RibbonFold is revolutionizing how scientists understand misfolded proteins linked to Alzheimer’s and Parkinson’s.

A first-of-its-kind gene therapy dramatically reduced misfolded protein levels in some clinical trial participants for up to six months and reduced levels in all participants for up to a year. Natalia ...

Dr Toby Ost, SVP of Product Development, Nuclera, said: "Membrane protein production has long been a technical challenge, ...

Medical testing laboratory Dr. Lal PathLabs said on Tuesday that it has become south Asia’s first diagnostic chain to offer ...