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Drug screening platform identifies compound for reinvigorating exhausted CAR-T cellsMoreover, in both allogeneic and syngeneic tumor models, miltefosine significantly enhanced the tumor-clearing capacity of CAR-T cells and T cells. The drug screening platform can assess FDA ...
However, several drugs that were developed for other purposes either directly or indirectly target PI3K signaling, such as the rapamycin analogs, the ether lipids perifosine and miltefosine ...
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