Each day, a human adult loses on average 50 to 70 billion cells, which die from natural causes alone. New cells replace lost ...

Microtubules tend to grow out from the centrosome to the plasma membrane. In nondividing cells, microtubule networks radiate out from the centrosome to provide the basic organization of the ...

The microtubule-associated protein XMAP215 promotes microtubule growth, but how this occurs has been unclear. To address this question, Gary Brouhard et al. developed a single-molecule ...

Kinetic measurements of kinesin-1's front and rear heads reveal how different neck linker orientation regulate their activity, enabling the motor protein to move in a coordinated manner along ...

BIIB080 is an antisense oligonucleotide therapy designed to target microtubule-associated protein tau mRNA and reduce the production of tau.