Figure 1: Plots of isotropic B factors calculated for protein structures solved in both the native and methylated states. We showed in this large-scale study that reductive methylation of proteins ...

DNA methylation is one of several epigenetic ... In an interestingly coordinated process, proteins that bind to methylated DNA also form complexes with the proteins involved in deacetylation ...

The protein is the MCJ (Methylation-controlled J) protein, and it was highlighted by a team led by researchers from the Spanish National Cancer Centre (CNIO). They also found a previously undiscovered ...

View Full Profile. Learn about our Editorial Policies. “This study really provides the first look at how methylation and epigenetic modification of the DNA eventually have an impact on the protein ...

In addition to finding that H3 lysine-4 methylation is important for activation of master regulator genes, McKay and colleagues also found that it plays a key role in turning "off" the protein ...

In the Protein Engineering and Evolution Unit's latest publication in Nucleic Acids Research, the team presents an engineered RNA methyltransferase, which can be used to study the role of RNA ...

A DNA methylation test is one of several noninvasive biomarkers test under investigation for the early diagnosis of bladder cancer.

A urinary DNA methylation test demonstrated a high sensitivity for detecting high-grade or invasive bladder cancer, ...