资讯

Nature4 年
DNA methylation and gene silencing
Post implantation, de novo methylation begins (red circles), mediated primarily by DNA (cytosine-5-)-methyltransferase-3alpha (DNMT3A) and -3beta (DNMT3B) (top). When methylation affects CpG ...
The Scientist2 年
Brush Up: What Is Bisulfite Sequencing and How Do Researchers Use It to Study DNA Methylation?
DNA methylation is a fundamental epigenetic mechanism in which a methyl group is added onto a nucleotide, commonly cytosine. DNA methylation affects many biological processes, including gene ...