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A study led by Umeå University, Sweden, presents new insights into how stem cells develop and transition ... for other proteins that control DNA methylation. The researchers were able to see ...
A new study reveals how the Dnmt3a mutation drives blood stem cell overgrowth, contributing to clonal hematopoiesis and ...
This study provides valuable findings on the role of site-specific DNA methylation changes during spermatogenesis and their contribution to paternal epigenetic inheritance. The study proposes that ...
“H3K36 methylation seems to be directly involved in differentiating the cells, but if you take it away, the cells revert to this regenerative stem cell state,” Dempsey says. “That ...
Researchers can now generate brain cells from patients using stem cells, which gives them a clearer understanding of how schizophrenia develops Individuals with schizophrenia may have abnormally ...
Researchers from the University of Colorado Cancer Center have solved a cellular mystery that may lead to better therapies for colorectal and other types of cancer. Peter Dempsey, PhD, professor ...
A gene involved in DNA methylation, a process that regulates gene expression. Mutations in DNMT3A are commonly observed in blood disorders, including leukemia. To further explore these findings, the ...
We apply both precision gene editing and large-scale CRISPR screening in human pluripotent stem cells (hPSCs) to explore mechanisms underlying human development ... and to understand the epigenetic ...
His parents enrolled him in a study that was collecting and storing immature testicular tissue, and the sperm-forming stem cells in them, from young patients with the goal of eventually giving ...
As we age, blood stem cells, the essential source of new blood cells in the body, can accumulate genetic mutations. These mutations can give the cells a growth advantage, laying the foundation for ...
If you buy through a BGR link, we may earn an affiliate commission, helping support our expert product labs. A man who was fully paralyzed is now able to stand after receiving an injection of ...