IT has been demonstrated that, besides heparin and histamine, mast cells contain serotonin (5-hydroxytryptamine, 5-HT) 1–3. However, serotonin-containing mast cells, having been found ...

and how histamine relates to mast cell activation syndrome, or MCAS, below. Histamine is a substance that naturally occurs in ...

is a condition in which mast cells—a type of white blood cell that plays a key role in the immune system—release excessive ...

Mast Cell Stabilizers Drugs like cromolyn sodium prevent histamine release by mast cells, a type of immune cell that responds to “foreign” substances, including some foods, by releasing histamine.

Mast cells are a key component behind itchy, irritated skin. They make the chemical histamine. How this histamine response results in a rash or flare of your other skin conditions is still unclear.

mast cells, eosinophils, neutrophils, macrophages, lymphocytes) and mediators (eg, histamine, eicosanoids, leukotrienes, cytokines) involved in inflammation. The pharmacologic effects of beta 2 ...