Mast cell activation syndrome ... called mediators, from their granules in a process known as degranulation. These mediators, which include chemicals such as histamine, cause an inflammatory ...

These granules are released upon encountering potential ... forming a cell-in-cell structure that the researchers refer to as ...

Mast cells are filled with tiny packages, or granules, each brimming with histamine ... anaphylaxis. In a previous Cell paper, Kaplan and his team found that neurons in the skin release a ...

Since corticotropin-releasing hormone, sensory nerves and mast cell numbers are increased in the psoriatic lesion, a feedforward loop can exist potentiating the inflammation. Studies in rats and ...