Mast cell activation syndrome ... from their granules in a process known as degranulation. These mediators, which include chemicals such as histamine, cause an inflammatory cascade.

Sure enough, they found that SYM2081 effectively suppressed mast cell degranulation and proliferation in both mice and human skin samples. And when the mice received a topical cream containing ...

Mast cell mediators, histamine, tryptase and NGF, released upon activation can excite sensory nerves and promote their growth. Corticotropin-releasing hormone, sensory nerves and the number of ...

Studies have shown that cromolyn sodium inhibits the degranulation of sensitized ... (slow-reacting substance of anaphylaxis) from the mast cell. Management of bronchial asthma in adults and ...