接下来,这个研究团队发现,抓挠会导致痛觉神经元释放一种名为P物质的化合物。反过来,P物质会激活肥大细胞,而肥大细胞是炎症的关键协调者,通过招募中性粒细胞来驱动瘙痒和炎症。
总的来说,搔抓与免疫反应的关系揭示了皮肤免疫疾病治疗的新方向。通过深入理解神经免疫交互作用,未来的研究有望开发出更加精确的治疗方法,不仅改善患者的临床症状,还可能从根本上恢复皮肤免疫功能。这一全新的治疗思路为过敏性皮肤病的管理带来了前所未有的希望,未 ...
Mast cell activation syndrome (MCAS) is a condition in which mast cells—a type of white blood cell that plays a key role in ...
Scratching an itchy rash worsens inflammation by triggering pain-sensing neurons and activating mast cells, creating a ...
Third Harmonic Bio, Inc. (NASDAQ:THRD) revealed results from its Phase 1 single and multiple ascending dose (SAD/MAD) trial ...
Scratching an itchy rash really does make it worse. Now we know why, thanks to new research published today in the journal ...
An itchy rash can be frustrating, and scratching often feels like the only relief. However, new research confirms that giving ...
The MAD cohort also saw adverse events such as hair loss and reductions in hemoglobin and neutrophil counts. These side ...
Scratching an itch can bring a contradictory wave of pleasure and misery. A mouse study on scratching, reported in the Jan. 31 Science, fleshes out this ...