Mast cell activation syndrome, or disease (MCAS), is a condition that causes mast cells to release these substances too frequently, resulting in severe allergic reactions. After detecting an ...

"That's what an allergic response is, it's activation of mast cells by an allergen, causing symptoms from release of histamine, leukotrienes, and other mediators," she added. In the case of hay fever, ...

may be used to prevent mast cell activation and the subsequent release of inflammatory mediators. Topical or oral ...

Caroline Cray was diagnosed with mast cell activation syndrome in May 2019 after repeated anaphylactic episodes Jordan Greene is Society and Culture writer-reporter at PEOPLE. She has been working ...

Mast cell mediators, histamine, tryptase and NGF, released upon activation can excite sensory nerves and promote their growth. Corticotropin-releasing hormone, sensory nerves and the number of ...