An increase in high-fat, high-fructose foods in people's diets has contributed to a dramatic increase in type 2 diabetes.

The duo were the first researchers to identify the disease-specific reprogramming of macrophages in cancer. TAMs are the most abundant immune cell in many types of cancer and modulating their ...

肝脏巨噬细胞在调节肝细胞代谢和维持肝脏免疫耐受方面发挥核心作用。正常生理条件下，肝脏巨噬细胞倾向于 M2 表型，可通过分泌白细胞介素（IL）-4 和 IL-13 抑制炎症。然而，在 NAFLD 进展时，肝星状细胞激活、血液中脂多糖水平升高以及 FFA 激活炎症小体等变化，会刺激炎症发生，增加分泌促炎细胞因子的 M1 巨噬细胞比例。

Biomedical scientists at the University of California, Riverside have received a $3.7 million grant from the National Institutes of Health to study the role of sex-specific immune responses in obesity ...

Macrophages are immune cells that reside in and protect the lungs and are also recruited to the lungs in high numbers during injury or disease. They are key to the initiation and resolution of ...

Mitochondria, often seen as cellular powerhouses, play a surprising role in immune regulation. Researchers found that ...

alveolar macrophages, helped make a key finding that is prompting researchers to rethink the role of another immune protein ...

Researchers explore the cellular and molecular adaptations associated with human secondary lymphoid tissue in adults during ...

Inflammatory processes are the body’s defence against local damage and disease. Inflammation involves the influx into organs of immune cells (white blood cells) from the blood. These cells deal with ...

Pancreatic cancer patients may benefit from future precision treatments as a new study shows how some tumors may potentially be more susceptible to macrophage-based therapies, and clues behind why ...