MHC分为I类和II类，分别负责呈递内源性和外源性抗原，进而介导CD8+和CD4+ T细胞相关的免疫反应。近年来，基于TCR的靶向肽-MHC复合体的免疫治疗方案 ...

Figure 1: MHC class II expression is reduced in HCMV-infected cells. Figure 2: US2 induces degradation of class II-α chains by proteasomes without a cytoplasmic intermediate and binds to class II ...

The importance of these studies cannot be exaggerated as they demonstrate the effectiveness of the immune system with spontaneous ... response to MHC class II molecules for provision of T-cell ...