MHC分为I类和II类,分别负责呈递内源性和外源性抗原,进而介导CD8+和CD4+ T细胞相关的免疫反应。近年来,基于TCR的靶向肽-MHC复合体的免疫治疗方案 ...
Figure 1: MHC class II expression is reduced in HCMV-infected cells. Figure 2: US2 induces degradation of class II-α chains by proteasomes without a cytoplasmic intermediate and binds to class II ...
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