Researchers explore the cellular and molecular adaptations associated with human secondary lymphoid tissue in adults during ...

Innate lymphoid cells (ILCs) are immune cells that belong to the lymphoid lineage but do not express antigen-specific receptors. These cells have important functions in innate immune responses to ...

胰腺癌（Pancreatic Ductal Adenocarcinoma, PDAC）因其高度侵袭性和极低的生存率，被认为是最具挑战性的癌症之一。尽管近年来免疫治疗技术迅速发展，许多肿瘤仍然被归类为“免疫冷”的状态，意味着肿瘤微环境中缺乏足够的免疫细胞浸润，使得治疗效果受限。然而，研究人员近年来的研究揭示了一个可能突破这一瓶颈的关键——三级淋巴结构（Tertiary Lymphoid Struct ...

This may result in the histologic diagnosis of AtLP – that is, lymph nodes with distorted architecture and lymphoid cells with worrisome cytological features – but findings are not sufficient ...

Vinod Balachandran identified the molecular pathway involved in the formation of tertiary lymphoid structures. Therapeutically targeting this pathway could potentially enhance the immune response to ...

Lymphoid proliferations are traditionally thought to be either benign conditions (reactive hyperplasia and lymphadenitis) or malignant lymphomas. However, not all lymphoid lesions at present can ...

WEDNESDAY, Jan. 22, 2025 (HealthDay News) -- A set of chameleon-like immune cells could be contributing to severe asthma in some patients. Intermediate group 2 innate lymphoid cells (ILC2s) appear to ...

The FSR Pilot Grant program, initiated in 2018, seeks to fund innovative research in both clinical and basic science settings ...

Previous research published in Nature by Dr. Balachandran's team found that an unusual type of immune cell called group 2 innate lymphoid cells (ILC2s) might have anti-cancer effects in pancreatic ...

But in recent years, the barrier between the branches has started to blur. As a postdoctoral fellow, Martinez-Gonzalez investigated the memory potential of another innate immune cell, type 2 innate ...