UNIGE Scientists have discovered an enzyme in cancerous lymphatic cells whose properties enable the immune system to fight ...
Researchers at the University of Geneva found that an enzyme in these vessels supports immune cells during anti-tumor ...
淋巴管肌瘤病(LAM)列为国家首批罕见病目录,是一种罕见的、主要发生在育龄期女性的低度恶性肿瘤,以肺部囊性改变为其显著特征。该疾病的发病机制与TSC2基因变异导致的mTOR通路过度激活相关。mTOR抑制剂雷帕霉素是治疗LAM的首个有效治疗药物,然而,迫切需寻找新的治疗方法。中国医学科学院北京协和医院的徐凯峰教授与中国 ...
With the identification of specific growth factors for lymphatic endothelial cells and markers that distinguish blood and lymphatic vessels, as well as the development of invivo imaging ...
In mice, MSC inhibit activation and proliferation of endothelial cells in remote inflamed lymph nodes (LNs), affect elongation and arborization of high endothelial venules (HEVs) and inhibit T ...
For 10 years, Karina Yaniv has worked to find out just how much zebrafish have in common with mice—at least when it comes to their lymphatic systems, the open-ended networks of vessels best known for ...
By performing RNA sequencing on the mice coupled with cell-based studies, the investigators observed that the activation of ...
Many cells comprise the tumor microenvironment, but endothelial cells are particularly crucial ... knew that NECs need to have a variety of gene expression patterns to specialize as venous, arterial, ...