guidelines recommend that intravenous unfractionated heparin (UFH) be dosed by weight with a bolus dose of 60 U/kg to a maximum of 4000 U and an infusion dose of 12 U/kg/h to a maximum of 1000 U/h.

This lowered the calculated dose for patients who were of large body size. The ACTION metric was based on actual body weight. Yet, the risk related to bleeding from excess dosing of heparin is ...

Low molecular weight heparin (LMWH ... While similar in mechanism to unfractionated heparin, LMWH is cleared renally, has a much longer half-life and less commonly causes heparin-induced ...