近期,北京工业大学化学与生命科学学院等单位的研究人员在Scientific Reports杂志上发表了题为 “BRISC inactivation alleviates alcohol-induced liver injury in mice” 的研究论文。该研究首次揭示了 BRCC3 异肽酶复合物(BRISC)在酒精性肝病(ALD)发展过程中的关键作用,为 ALD 的 ...
Scientists at EMBL and DKFZ have discovered how cells in the liver maintain their identity and avoid becoming tumour cells ...
We tested our new drug on mice with liver damage from toxic doses of Tylenol. We found that one dose was able to decrease ...
A new study reveals that even low-dose, chronic exposure to air pollution can trigger liver inflammation, fibrosis, and metabolic disruptions, increasing the risk of fatty liver disease and other ...
Drug-induced liver injury (DILI) is common because it can be caused by different pharmacological agents from nearly all classes of medications, including hepatotoxic drugs, anesthetics, anticancer ...
but not male mice, experienced reduced hepatic protoporphyrin accumulation and liver injury, decreased protoporphyrin in bone marrow and red cells and increased protoporphyrin excretion in stool.
Mice fed a high-fat ... not only in reducing liver injury but also in restoring cellular health. The study’s findings underscore the critical role of NAD+ in maintaining liver function and ...
and bone marrow of female mice while promoting stool excretion of PP-IX. Plasma biomarkers of liver injury, such as alanine aminotransferase (ALT) and alkaline phosphatase (ALP), were also reduced ...
but not male mice, experienced reduced hepatic protoporphyrin accumulation and liver injury, decreased protoporphyrin in bone marrow and red cells and increased protoporphyrin excretion in stool.