撰文丨王聪编辑丨王多鱼排版丨水成文药物性肝损伤（Drug-induced liver injury，DILI）涉及多方面的发病机制，需要有效的治疗策略。肝窦内皮细胞（LSEC）分泌的 Wnt2 可激活 Wnt/β-catenin ...

Bile duct inflammation and scarring, known as cholangiopathies, can disrupt bile flow, leading to liver damage and ...

However, upon liver injury, as seen, for example ... "We used several advanced research methods, such as single-cell RNA sequencing and spatial transcriptomics, to investigate the heterogeneity ...

High levels of ammonia kill liver cells by damaging the mitochondria that power the cells. But this can be prevented using an existing drug due to start clinical trials, finds a new study in mice.

For the first time, researchers outline new therapeutic avenues for a rare patient group with unmet clinical needs, paving ...

research on the liver's stellate cells has focused on their role in driving diseases that scar the liver. "Evolutionary ...

The paradigm of stellate cell activation provides an important ... but not self-limited liver injury. Ultimately, hepatic fibrosis leads to cirrhosis, characterized by nodule formation and organ ...

Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type ...