The Mt. Sinai study could open the door to future therapies for Alzheimer’s, amyotrophic lateral sclerosis, brain cancer, and ...

Our data show as a proof-of-principle that psychotropic drug-induced stimulation of cellular lipid biosynthesis ... of cholesterol transport and -efflux, including ApoE. Such drug-effects could ...

Apolipoproteins (apo) such as apoB, apoC and apoE, coat lipoprotein particles and serve a number of functions including the transport of lipids in the blood and recognition of lipoprotein ...

Apolipoprotein E (apoE), a crucial glycoprotein in CNS lipid metabolism, particularly its apoE4 isoform, significantly influences AD pathogenesis by affecting lipid-binding properties and impairing Aβ ...

Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering ...

Analyzing the lipids and related proteins in the bone marrow of anemic mice showed that although VLDL levels decreased, ...