Hu-Mikβ1 was evaluated in a Phase I clinical trial in patients with T-cell large granular lymphocyte leukemia. Hu-Mikβ1 was shown to be safe in Phase I trials; however, no therapeutic efficacy ...

Previous studies have shown that IL-15 is critical to the induction of T-cell large granular lymphocyte (T-LGL) leukemia. A Phase I trial of a humanized antibody (Hu-Mikβ1) to the IL2/IL15Rβ ...

When a lymphocyte encounters that antigen it multiplies, creating large numbers of identical lymphocytes bearing that particular receptor. Antibodies and antitoxins are highly specific to the ...

Lymphocyte differentiation is a process in which activated B cells or T cells become specialized immune cells. For example, B cells can give rise to antibody-producing cells and T cells can ...

Background The neutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammation associated with adverse ...