Germ-free (GF) mice have reduced adiposity and are protected against diet-induced obesity, Objective To investigate whether the gut microbiota and, specifically, gut-derived lipopolysaccharide (LPS) ...

Macrophages display a diverse set of ‘scavenger receptors’ that bind bacterial lipopolysaccharides (LPS), phospholipids inappropriately exposed on apoptotic cells and oxidized forms of LDL ...

This study unveiled the role of Lrrk2 gene in regulating macrophage polarization and immune response. This finding provides ...

Nevertheless, the genome-wide impact of SeMC on gene transcription remains to be elucidated. In this study, we employed an LPS-stimulated chicken HD11 macrophage-like cell model to identify the ...

3 Macrophages in the presence of interferon-γ and lipopolysaccharide (LPS), what is known as classical activation, acquire an inflammatory phenotype and are also termed M1 macrophages. On the other ...

Methods Human monocyte-derived macrophages (MDMs) were stimulated with lipopolysaccharide (LPS) or plasma samples from patients with ARDS (these samples were previously classified into ...

Conclusions—Exposure of normal colonic macrophages to LPS only induces the production of the precursor form of IL-1β, because the cells fail to activate ICE. In contrast, IBD colonic macrophages are ...

samples were collected from mice with or without intratracheal lipopolysaccharide (LPS) instillation. BALF MVs were characterised and MV-containing microRNA (miRNA) profiles were assessed and ...

It was recently shown that stimulation of RAW264.7 murine macrophages by LPS, LAM, STF, and PIM rapidly activated NF-κB, AP1, and MAP kinases. RESULTS This study shows that signalling by TLR2 and TLR4 ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Pro-inflammatory macrophage activation is a ...

Mouse bone marrow-derived macrophages were treated with indicated activators and incubated during the ... Experiments were performed as previously described (Derangere et al., 2014). Cells were ...