The earliest changes in stellate cells are likely to result from paracrine stimulation by all neighboring cell types, including sinusoidal endothelium, Kupffer ... cell type in liver, are a ...

He was actually observing two distinct cell types: Kupffer cells (liver macrophages) and hepatic stellate cells (which activate during liver injury to produce scar tissue). “Given the complexity ...

In the healthy liver, most macrophages are classified as Kupffer cells (KCs). However, upon liver injury, as seen, for example, in obesity, another subset of macrophages called lipid-associated ...

HHMI researchers solve a longstanding mystery about the origin of new cells in the liver. Howard Hughes Medical Institute (HHMI) scientists have identified stem cells in the liver that give rise to ...

and key mediators of liver disease progression. LncRNAs influence several metabolic pathways in hepatocytes, hepatic stellate cells (HSCs), and Kupffer cells, impacting lipid metabolism ...

Ammonia buildup damages liver cells by harming mitochondria, leading to cell death and liver injury. An existing drug, YAQ-005, can prevent this damage by halting mitochondrial harm, allowing ...

High levels of ammonia kill liver cells by damaging the mitochondria that power the cells. But this can be prevented using an existing drug due to start clinical trials, finds a new study in mice.

Because of this, the information in this primary liver cancer section is mostly about hepatocellular carcinoma. This type of liver cancer develops from the main liver cells called hepatocytes. It's ...