In vivo studies then demonstrated the ability of both anti-TNF siRNA modified with 2'-O-methyl nucleotides and unmodified anti-TNF siRNA administered by intraperitoneal injection to transfect and ...

Mice were fully anesthetized by intraperitoneal injection of ketamine and xylazine, and their abdominal skin was shaved using a hair-clipper before powder delivery. For EI, the PowderJect ND ...