腰痛已成为全球性的重大健康问题，给社会带来了沉重的经济负担，并且随着人口老龄化的加剧，这一问题愈发严重。众多研究表明，腰痛与椎间盘退变密切相关。椎间盘退变过程中，髓核细胞（nucleus pulposus cells，NPCs）和细胞外基质（extracellular matrix，ECM）会逐渐流失。细胞外基质主要由胶原纤维和蛋白聚糖（如聚集蛋白聚糖）组成，主要由髓核细胞产生并维持，其中 ...

Degenerative ... disc disease is extremely rare. Intrigued by this fact and how it might apply to humans, researchers in Toronto, Canada, decided to conduct a gene expression study on ...

Objectives: To observe the prevalence of lumbar intervertebral disc degeneration in elite athletes as compared with published literature of changes seen in non-athletes—that is, normal population.