4). For all subjects, the stimulated area included the intraparietal sulcus and the adjacent cortex in the superior and inferior parietal lobule. Although the stimulated area varied slightly among ...

These findings provide some evidence that reduced slow wave sleep (SWS) and rapid eye movement sleep (REM) may contribute to brain atrophy, thereby increasing the risk of Alzheimer disease (AD).

Disrupted SWS (critical for waste clearance) and REM sleep (key for memory) may impair the glymphatic system, hindering the removal of Alzheimer’s-linked beta-amyloid plaques. The study suggests sleep ...

There was an association between having less REM with smaller volumes of the inferior parietal region and precuneus (β = −75.54 and −31.92 mm 3 per −1 percentage point of REM, respectively).

particularly the inferior parietal region, which is known to undergo early structural changes in Alzheimer's disease. The results were adjusted for potential confounders including demographic ...