The opposite is true of a paternally imprinted gene. For imprinting to work, the epigenetic signal must be consistent in the mature gamete and the cells originating from the zygote that this ...

In short, imprinting of the same region on chromosome ... In each case, the presence of a second good copy of the gene(s) on the methylated, tightly packed copy of chromosome 15 is of no use ...

Gregg explains that for this gene, “If you lose the dad’s copy ... Dulac and Gregg both say that an obvious next step is to repeat the process looking at any of the several other genes that show signs ...

For example, DNA methylation modifies gene expression without altering the nucleotide sequence. A well-studied DNA methylation-based phenomenon is genomic imprinting (ie, genotype-independent ...